Our Lab studies how epigenetic alterations in immune and structural cells are altered in cardiovascular diseases and tissue regeneration processes and can be manipulated to improve treatment of patients with cardiovascular disease and impaired tissue repair.
The IECT Labs, led by Dr. Katherine Gallagher, works at the intersection of immunology, biomedical research, and cardiovascular medicine. The fields of immunotherapy and epigenetics have grown tremendously over the previous decade.
Although these areas have been more well studied in cancer, they are relevant for cardiovascular disease and can be specifically targeted using nanocarriers and other technology to modulate inflammation and other pathologic processes in cardiovascular disease and to aid in tissue repair processes.
Our group aims to translate our findings identifying important epigenetic pathways into therapeutic cell specific therapy for the treatment of patients with cardiovascular and cardiometabolic diseases.
Gallagher KA, Mills JL, Armstrong DG, Conte MS, Kirsner RS, Minc SD, Plutzky J, Southerland K, Tomic-Canic M.
Circulation 2024 Jan 23;149(4):e232-e253. 38095068
Bauer TM, Gallagher KA.
J Clin Invest 2024 Feb 1;134(3):e176547. Abstract 38299590
We are currently looking for new lab members! Master's, doctoral, and post-doctoral students are encouraged to apply.